Monkeys implanted with HUMAN BRAIN genes - with SHOCKING results
14 April, 2019, 16:07 | Author: Kelly Sanders
After implanting 11 monkeys with different versions of MCPH1, a gene considered key to the development of the human brain, the scientists concluded that, like humans, the brain of the tested monkeys took longer to develop and performed better in short-term memory and reaction time tests compared to wild monkeys. However, the scientific community raised ethical questions on the use of transgenic monkeys for experiments.
To mesh the human gene into the monkey genomes, the scientists injected viruses carrying the MCPH1 gene into monkey embryos and then allowed the monkeys to develop naturally.
Another Chinese researcher - the disgraced Professor He Jiankui - faced global condemnation after he told the world he had created the first gene-edited babies in November 2018.
Animal rights group PETA also did not favor the experiment, saying that genetic engineering is absolutely unethical and only increases animal suffering.
The experiment, which was conducted at the Kunming Institute of Zoology and the Chinese Academy of Sciences with the help of USA researchers at the University of North Carolina, involves inserting a human version of Microcephalin (MCPH1), a gene that is believed to play a role in the development of human brains, into the brains of 11 rhesus monkeys, according to AFP. These surviving monkeys were put through a barrage of cognitive tests, including memory tests and brain scans. In the future, similar research might enable scientists to develop treatments for diseases caused by abnormal brain development.
Bing Su, the geneticist at the Kunming Institute of Zoology who led the effort, said: "this was the first attempt to understand the evolution of human cognition using a transgenic monkey model".
Monkeys Made Smarter by Human Gene-Editing
Martin Styner of the University of North Carolina who's role in this experiment was limited to training students how to extract brain volume from MRI images says "There are a bunch of aspects of this study that you could not do in the U.S., it raised issues about the type of research and whether the animals were properly cared for." .
"You just go to the Planet of the Apes immediately in the popular imagination", bioethicist at University of Colorado, Jacqueline Glover, said while speaking to MIT Technology Review via AFP. "Do not create a being that can't have a meaningful life in any context".
Su says he is making more monkeys and is testing a new brain evolution gene called SRGAP2C, which is a gene variant that arose about 2 million years ago when Australopithecus was ceding in the African savannah to human, this gene has been dubbed the humanity switch and missing genetic link because of its likely role in the emergence of human intelligence. This study changed a few of those in just one of about 20,000 genes. "These harms render the conduct of this research ethically unacceptable in apes, justifying regulatory barriers between these species and all other non-human primates for transgenic research", Sikela and colleagues wrote at the time. "You can decide for yourself whether there is anything to worry about".
This experiment did not turn out well as the animals suffered mental problems including depression, anxiety, and behaviors linked to schizophrenia.
They said the study was meant to aid research into human psychological problems.
Kadri and John Tavares were denied on a Leafs' power play, and Zach Hyman hit the post as the visitors tried to respond. Jake Muzzin was bloodied by a hard David Pastrnak hit, and then delivered a thunderous check of his own on Torey Krug .
The Pistons needed to either win or have the Charlotte Hornets lose to the Orlando Magic to clinch the playoff berth. Dorian Finney-Smith was two-of-10 shooting and scored five points in the Mavericks' defeat.
Francesco also won the Arnold Palmer Invitational at Bay Hill earlier this season and was third at the recent WGC Match Play. After a flawless opening round, Koepka had two bogeys and a double in his first six holes on Friday but the twice U.S.
Gundogan had told Sky Deutschland: "We were not fearless enough in the game and we made a lot of simple mistakes". But we have six games left to finish the Premier League, and we know what we are playing for.
Brendan Rodgers insists his Leicester squad will learn from their disappointing home defeat to Newcastle on Friday. With the players we have, we'll work with them to open up the idea of where we can be better in that situation.
No arrests have been made so far. 4 people are in hospital, 2 of whom are critical after a shooting at the venue at 3:20am. Police are urging anyone with video footage of the incident or information to contact them.
The sheriff's office says the county saw other downed trees and power lines and minor structural damage from the storms. The most significant risk of severe weather is expected Saturday, but there's still considerable potential Sunday.
Winx's 43rd and final victory came in front of a sold-out crowd at Royal Randwick. "It's over", Waller said afterwards. Converted to U.S. dollars, Winx has now passed Arrogate (U.S.$17,422,600) as the world's all-time money victor .
Walton couldn't win with LeBron James but the rumors are they know just the man to get this team back to the playoffs. Beyond the early-season meeting, communication between Walton and the front office was fraught, sources told ESPN .
IS claims responsibility for attack in Pakistan’s Quetta
According to the report, Pakistan's Prime Minister Imran Khan condemned the blast and sought an inquiry report of the attack. Qadir Nayil, a leader of the Hazara community, asked the government to provide better protection for the Shiites.
Jewel Changi Airport opens in Singapore
As well as an attraction for visitors to Singapore, it is also billed as a destination in its own right for local residents. The majestic 40-metre HSBC Rain Vortex , the world's tallest indoor waterfall, will greet visitors upon entering Jewel.