The final Senate vote is expected Saturday afternoon.
Senator Joe Manchin, the only remaining undecided Democrat, said he would finish reading the report on Friday morning.
But when all the votes were cast, ultimately Murkowski voted no and Collins voted yes.
Murkowski did not directly link her decision on Kavanaugh's confirmation to the rate of sexual assault in Alaska, though she has spoken out about the issue previously and has introduced legislation to help victims of sexual assault.
North Dakota Senator Heidi Heitkamp, who faces a hard re-election race next month, cited concerns about his "past conduct" and said she felt his heated attacks on Democrats during last week's Judiciary Committee hearing raised questions about his "current temperament, honesty and impartiality".
Outside, protesters shouted "shame on you" as Manchin spoke to reporters about his decision. Manchin deployed the now-familiar line: "I believe Dr. Ford", he said.
"I think what Susan did today was rise to the occasion when the stakes were so high", said Sen.
Manchin says he has reservations because of the sexual misconduct accusations against Kavanaugh and the judge's temperament in denying them.
Senator Manchin, who is up for re-election in West Virginia, a traditionally Republican state that Mr Trump won by a landslide, told the senate moments later he "found Judge Kavanaugh to be a qualified jurist who will follow the constitution and determine cases based on the legal findings before him". More than 300 were arrested on Thursday.
Sen. Jeff Flake, R-Ariz., who's repeatedly battled Trump and will retire in January, said he'd vote for Kavanaugh's confirmation "unless something big changes".
But the drama wasn't over until Collins delivered a 45-minute speech explaining her reasons for supporting the president's nominee - primarily the importance of the American ideal that a person is innocent until proven guilty. McConnell then warned that he would up the ante and blow up the filibuster for Supreme Court nominees, and when he got in power, he did just that a year ago during the confirmation process for Neil Gorsuch.
In theory, Kavanaugh could be confirmed, sworn in and sitting on the mahogany bench in the traditional black justice's robe by Tuesday, when the court is next in session.
The Kavanaugh fight has riveted Americans just weeks before November 6 elections in which Democrats are trying to take control of the U.S. Congress from the Republicans.
"That should concern us all", said California Democrat Diane Feinstein, the ranking member of the Judiciary Committee.
In a speech leading up to the vote, Judiciary Committee Chairman Sen.
U.S. Sen. Rob Portman (R-OH) voted to advance the nomination to the Supreme Court.
Republicans hold a 51-49 majority in the Senate, meaning that if all Senate Democrats oppose Mr Kavanaugh, Mr Trump can not afford to lose more than one Republican vote for his nominee, with Vice President Mike Pence casting a tiebreaking vote.
"New information of a material nature regarding temperament during the September 27 hearing before the Senate Judiciary Committee has prompted a reopening of the Standing Committee's evaluation", reads the letter, Bloomberg reports.
Average hourly earnings are forecast to have increased 0.3 percent in September after leaping 0.4 percent in the prior month. The United States and China had already imposed tariffs on $50 billion worth of each other's goods.
Lisa Murkowski , on Friday for announcing her intent to vote "no" on Judge Brett Kavanaugh's confirmation to the Supreme Court . Democrat Joe Manchin voted for cloture, which meant that Vice President Pence did not have to be brought in to break a tie.
The Portugal global had previously said the allegation, first reported in German magazine Der Spiegel , was " fake news ". However, Nike and EA Sports, who both sponsor Ronaldo, have revealed they are "very concerned" by the allegations.
Peretti has been on the beloved sitcom since day one, playing apathetic office assistant and general shot-caller Gina Linetti . He said in his own statement that he and Mike Schur eyed Peretti for her role as Gina from the very beginning.
He asked the then-homeowner about it who told him it was a meteorite which the farmer had discovered on the property in the 1930s. Now the Smithsonian museum is considering buying the space rock, and it could fetch as much as $100,000, the release says.
Mike "The Situation" Sorrentino , best known for starring on MTV's " Jersey Shore ", has been sentenced to prison for tax evasion. He and his brother were charged for filing false tax returns for approximately $8.9 million in income between 2010 and 2012.
But, when Kohli reached the triple-digit figures, Pant already had 87 runs to his name and was himself aiming for a hundred. And at the end of day's play, Jadeja admitted what is meant for him scoring a hundred after nine years of global cricket.
McGregor recently signed a new six-fight deal with the UFC and he is already thinking ahead to what comes next after Nurmagomedov. With that said, the undefeated Russian sent a warning to the Irishman that he plans on changing his face at UFC 229 .
Dominant Clayton Kershaw puts Dodgers in command of NLDS
It took 163 games to sort it all out but the Dodgers just won their sixth straight NL West title after beating the Rockies 5-2. Ace pitcher Clayton Kershaw was expected to start Game 2 of the best-of-five series against the Braves' Anibal Sanchez .
Brett Kavanaugh poised for confirmation to Supreme Court
Senate, and with the two key senators choosing to vote in favor of Kavanaugh, the confirmation looked locked-in late on Friday. The president claimed billionaire financier George Soros, a frequent target of conservatives, was behind their demonstrations.
Twitter announces data saver setting in South Africa
If you want to view any content in full quality, you can just select drop-down menu in a tweet and choose "Load High Quality". At this point, most of us have enough data on our mobile phone plans that you don't have to track your usage by the megabyte.
JWoww and Roger Are No Longer DTF
I'm gonna win my wife back; I'm gonna win her affection back; I'm gonna win her love back. 'I am going to win my wife back. Farley has starred in MTV's original Jersey Shore , which ran from 2009 to 2012 and was filmed in Seaside Heights.
Doorstop turns out to be meteorite worth $100K
A man has discovered a rock he's been using as a doorstop for 30 years is actually worth more than A$140,000. A man has discovered that a rock he's been using as a doorstop for 30 years is a meteorite worth $100,000.